A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of City Museum and Enterprise Center. This luxury hotel is 0.6 mi (1 km) from St. Louis Union Station and 0.7 mi (1.1 km) from America's Center Convention Complex.

Make yourself at home in one of the 104 air-conditioned rooms featuring espresso makers and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.

Don't miss out on the many recreational opportunities, including an indoor pool, a steam room, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and a banquet hall.

Enjoy a meal at the restaurant or snacks in the coffee shop/cafe. The hotel also offers room service (during limited hours). Wrap up your day with a drink at the bar/lounge. Cooked-to-order breakfasts are available daily from 6:30 AM to 1:00 PM for a fee.

Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk.

• Extra-person charges may apply and vary depending on property policy
• Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
• Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
• This property accepts credit cards; cash is not accepted
• Safety features at this property include a smoke detector and outdoor lighting

Front desk staff will greet guests on arrival at the property.

• Reservations are required for massage services. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation.
• This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

• Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

• Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
• Valet parking fee: USD 50 per day (in/out privileges)
• Pet fee: USD 100 per accommodation, per stay
• Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.